Primary effusion lymphoma.

  title={Primary effusion lymphoma.},
  author={Yi-Bin Chen and Aliyah Rahemtullah and Ephraim P. Hochberg},
  journal={The oncologist},
  volume={12 5},
Primary effusion lymphoma (PEL) is a rare HIV-associated non-Hodgkin's lymphoma (NHL) that accounts for approximately 4% of all HIV-associated NHL. PEL has a unique clinical presentation in having a predilection for arising in body cavities such as the pleural space, pericardium, and peritoneum. PEL cells are morphologically variable with a null lymphocyte immunophenotype and evidence of human herpesvirus (HHV)-8 infection. The exact oncogenic mechanisms of HHV-8 have not been clearly defined… CONTINUE READING


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