Primary defect of juvenile visceral steatosis (jvs) mouse with systemic carnitine deficiency is probably in renal carnitine transport system.

Abstract

We investigated the reabsorptional system for carnitine in the kidney to elucidate the mechanism of carnitine deficiency in juvenile visceral steatosis (jvs) mice. Jvs mice had a higher rate of carnitine excretion at 10 days after birth than the controls, in spite of having no pathological acylcarnitine excretion in the urine. In an experiment to assay the… (More)

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@article{Horiuchi1994PrimaryDO, title={Primary defect of juvenile visceral steatosis (jvs) mouse with systemic carnitine deficiency is probably in renal carnitine transport system.}, author={Marika Horiuchi and K. Kobayashi and S. Yamaguchi and Naoki Shimizu and Tomonobu Koizumi and Hirofumi Nikaido and Jun Hayakawa and Masaaki Kuwajima and T. Saheki}, journal={Biochimica et biophysica acta}, year={1994}, volume={1226 1}, pages={25-30} }