Primary cultures of neonatal rat liver as an assay system to identify compounds belonging to the tumor promoters class.

Abstract

A single exposure to a low concentration (10-10 mol/L) of tumor promoters (like 12-0-tetradecanoylphorbol-13-acetate (TPA), phenobarbital, and nafenopin) or of hormones (as epidermal growth factor (EGF), glucagon and insulin) or of drugs (like imidazole and indomethacin) stimulated the 24-h flow into DNA synthesis and mitosis of primary neonatal rat… (More)

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Cite this paper

@article{Marigo1985PrimaryCO, title={Primary cultures of neonatal rat liver as an assay system to identify compounds belonging to the tumor promoters class.}, author={Andrea Marigo and Paola G. Andreis and Flora Romano and Gianni Cavatton and Ubaldo Armato}, journal={Developments in biological standardization}, year={1985}, volume={60}, pages={371-91} }