Primary cultures of fetal hepatocytes from the genetically obese Zucker rat: Characterization and total lipogenesis

@article{Goldstein1980PrimaryCO,
  title={Primary cultures of fetal hepatocytes from the genetically obese Zucker rat: Characterization and total lipogenesis},
  author={Allan L. Goldstein and Patricia R Johnson},
  journal={In Vitro},
  year={1980},
  volume={16},
  pages={288-296}
}
Primary fetal hepatocyte cultures derived from Zucker rats and with expectedfa-gene frequencies of 0.0 and 0.75 have been established and can be used to detect early effects of thefa gene on hepatocellular metabolism. Proliferative capacity is similar in both types of culture. Changes of the growth media significantly decrease total lipogenesis in both 0.0… CONTINUE READING