Primary cortical representation of sounds by the coordination of action-potential timing

  title={Primary cortical representation of sounds by the coordination of action-potential timing},
  author={R. Christopher DeCharms and Michael Merzenich},
CORTICAL population coding could in principle rely on either the mean rate of neuronal action potentials, or the relative timing of action potentials, or both. When a single sensory stimulus drives many neurons to fire at elevated rates, the spikes of these neurons become tightly synchronized1,2, which could be involved in 'binding' together individual firing-rate feature representations into a unified object percept3. Here we demonstrate that the relative timing of cortical action potentials… 

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Effectiveness of synaptic transmission, measured by the peak area of cross-correlations between input and output spikes, increased with increasing synchrony, and could reduce firing rate for higher values of the three parameters.

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