Primary chronic myelofibrosis: clinical and prognostic evaluation in 336 Japanese patients.

@article{Okamura2001PrimaryCM,
  title={Primary chronic myelofibrosis: clinical and prognostic evaluation in 336 Japanese patients.},
  author={Tomohisa Okamura and Naoko Kinukawa and Yoshiyuki Niho and Hideaki Mizoguchi},
  journal={International journal of hematology},
  year={2001},
  volume={73 2},
  pages={194-8}
}
We retrospectively analyzed 336 patients with primary chronic myelofibrosis from 203 medical institutes in Japan. Notwithstanding their heterogeneous treatments, the median survival in 298 patients that could be evaluated was 10.0 years. Average age at onset was 60.7 years. Men were affected 1.4 times more frequently than women. The factors associated with shorter survival included anemia, leukocytosis/leukocytopenia, thrombocytopenia, and increased blasts in the peripheral blood, and sex (male… CONTINUE READING