Primary central nervous system post-transplant lymphoproliferative disorders following allogeneic hematopoietic stem cell transplantation

@article{Lieberman2011PrimaryCN,
  title={Primary central nervous system post-transplant lymphoproliferative disorders following allogeneic hematopoietic stem cell transplantation},
  author={Frank Lieberman and Victor Y Yazbeck and A. D. Raptis and Raymond E. Felgar and Michael Boyiadzis},
  journal={Journal of Neuro-Oncology},
  year={2011},
  volume={107},
  pages={225-232}
}
Post-transplant lymphoproliferative disorder (PTLD) is a serious complication after allogeneic hematopoietic stem cell transplantation (HSCT). Extra nodal involvement is common in PTLD, but isolated involvement of the central nervous system (CNS) is extremely rare. Given the rarity of primary CNS-PTLD there is no consensus on optimal treatment. We report a patient who developed Epstein-Barr virus related primary CNS-PTLD following allogeneic HSCT who was treated with the monoclonal anti-CD20… CONTINUE READING

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