Primary central nervous system lymphoma in the elderly: a multicentre retrospective analysis.

@article{Schuurmans2010PrimaryCN,
  title={Primary central nervous system lymphoma in the elderly: a multicentre retrospective analysis.},
  author={Mascha Schuurmans and Jacoline E. C. Bromberg and Jeanette Doorduijn and Philip Poortmans and Martin J. B. Taphoorn and Tatjana Seute and Roelien H. Enting and Gustaaf W van Imhoff and Yvette van Norden and Martin J van den Bent},
  journal={British journal of haematology},
  year={2010},
  volume={151 2},
  pages={
          179-84
        }
}
Elderly patients with primary central nervous ystem lymphoma (PCNSL) do not tolerate treatment with combined radio-chemotherapy well because of leuco-encephalopathy; they are usually treated initially with chemotherapy or radiotherapy alone. Little is known about the efficacy and toxicity of these treatments outside clinical studies. This study was a retrospective analysis of all patients aged 60 years or over who were admitted with PCNSL to one of five Dutch centers between 1998 and 2007. A… CONTINUE READING

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