Primary cell cultures from fetal bovine hypothalamus and cerebral cortex: a reliable model to study P450Arom and alpha and beta estrogen receptors in vitro.


Estrogens synthesized by neural P450 aromatase (P450Arom) are implicated in many aspects of mammalian brain development and particularly in sexual differentiation of the central nervous system (CNS). This study analyzes the usefulness of an in vitro model based on bovine primary cell cultures from the hypothalamus and frontal cortex to investigate the role… (More)
DOI: 10.1016/j.neulet.2008.01.047


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