Primary biliary cirrhosis once rare, now common in the United Kingdom?

@article{James1999PrimaryBC,
  title={Primary biliary cirrhosis once rare, now common in the United Kingdom?},
  author={Oliver F. W. James and Raj S Bhopal and Denise Howel and Jackie Gray and Alastair D. Burt and Jane V Metcalf},
  journal={Hepatology},
  year={1999},
  volume={30}
}
There is a widespread impression that the number of patients with the autoimmune liver disease primary biliary cirrhosis (PBC) is increasing, although its incidence and prevalence vary widely. Using thorough case‐finding methods and rigorous definitions to assess changes in incidence and prevalence with time and to explore the symptomatology and mortality of the disease in a large group of unselected patients, we performed a descriptive epidemiological study of PBC in a well defined population… 
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Is primary biliary cirrhosis rare or common? The truth lies somewhere in between
  • E. Rigopoulou, D. Bogdanos
  • Medicine
    Liver international : official journal of the International Association for the Study of the Liver
  • 2014
TLDR
Data is presented from the largest up to the present population-based study conducted in Holland on the prevalence and incidence of primary biliary cirrhosis and the use of ursodeoxycholic acid has been shown to improve survival in patients with stage I and II disease, similar to that reported in the general population.
Low incidence and prevalence of primary biliary cirrhosis in Canterbury, New Zealand: a population-based study
TLDR
This first population-based epidemiological study of PBC conducted in New Zealand and only the second in the Southern Hemisphere has provided further support to the hypothesis that there may be a protective effect or lack of a risk factor for PBC inNew Zealand.
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