Primary biliary cirrhosis: clinical features and outcome, with special reference to asymptomatic disease.


The clinical features and outcome of primary biliary cirrhosis (PBC) during long-term follow-up study (mean, 9 years; range, 1-20 years) was reviewed in 80 patients. Seventy per cent were asymptomatic at initial presentation. The mortality in the symptomatic group was 63%, compared with 20% in the asymptomatic group (p less than 0.001). The presence of… (More)