Primary autosomal recessive microcephaly: homozygosity mapping of MCPH4 to chromosome 15.

  title={Primary autosomal recessive microcephaly: homozygosity mapping of MCPH4 to chromosome 15.},
  author={C. Jamieson and C. Govaerts and M. Abramowicz},
  journal={American journal of human genetics},
  volume={65 5},
  • C. Jamieson, C. Govaerts, M. Abramowicz
  • Published 1999
  • Biology, Medicine
  • American journal of human genetics
  • To the Editor: Microcephaly is a condition in which the head circumference is smaller than <3 SD below the mean for age. Syndromic microcephaly is found in a number of environmental, chromosomal, or single-gene disorders. Nonsyndromic, isolated microcephaly is also etiologically heterogeneous, and micrencephaly—that is, a generalized reduction of the brain mass causing a small skull without craniosynostosis—appears as a distinct subtype within this group. When micrencephaly is the only or… CONTINUE READING
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