Primary antiphospholipid syndrome: a low-grade auto-inflammatory disease?

@article{Ames2008PrimaryAS,
  title={Primary antiphospholipid syndrome: a low-grade auto-inflammatory disease?},
  author={Paul Rj Ames and Iole Antinolfi and Antonio da Costa Ciampa and Joana Rita Batuca and Giovanna Scenna and Leidy Rosselli Rojas L{\'o}pez and Jos{\'e} Delgado Alves and Luigi Iannaccone and Eiji Matsuura},
  journal={Rheumatology},
  year={2008},
  volume={47 12},
  pages={
          1832-7
        }
}
OBJECTIVE To test the inflammation and immune activation hypothesis in primary thrombotic APS (PAPS) and to identify clinical and laboratory factors related to inflammation and immune activation. METHODS PAPS (n = 41) patients were compared with patients with inherited thrombophilia (IT, n = 44) and controls (CTR, n = 39). IgG aCL, IgG anti-beta2-glycoprotein I (beta(2)GPI), high-sensitivity CRP (hs-CRP), serum amyloid A (SAA), CRP bound to oxidized low-density lipoprotein-beta(2)GPI complex… CONTINUE READING

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