Primary antibody response studied by using inhibitors of nucleic acid synthesis

Abstract

Inhibitors of nucleic acid synthesis were tested for the effect on the primary antibody response. Antibody formation by adult spleen cells mixed with antigenin vitro and transferred to newborn rabbits was completely suppressed by 6-mercaptopurine administered in the initial phase of antibody induction. The extent of inhibition decreased proportionately to… (More)
DOI: 10.1007/BF02878838

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