Primary and recurrent Crohn's disease. Experience with 1379 patients.

  title={Primary and recurrent Crohn's disease. Experience with 1379 patients.},
  author={Fabrizio Michelassi and Tommaso Balestracci and Richard H. Chappell and George E. Block},
  journal={Annals of surgery},
  volume={214 3},
  pages={230-8; discussion 238-40}
Between 1970 and 1988, 1379 patients with Crohn's disease were treated at the University of Chicago. Of these, 639 (mean age, 32.5 years; 322 men, 317 women) required at least one surgical procedure. The most common indications for operation were failure of medical treatment (n = 215, 33%), presence of a fistula (n = 154, 24%), and bowel obstruction (n = 141, 22%). A fistula was the most common intraoperative Crohn's-related complication. In 582 patients (92%), a resection was necessary, with… CONTINUE READING