Primary amebic meningoencephalitis.

  title={Primary amebic meningoencephalitis.},
  author={C. Butt},
  journal={The New England journal of medicine},
  volume={274 26},
  • C. Butt
  • Published 1966
  • Medicine
  • The New England journal of medicine
THE following 3 case studies, related experimental data and review of the recent literature introduce a new clinical concept, that of primary meningoencephalitis due to the the free-living, soil ameba, commonly referred to as acanthameba (species). It is suggested that in these 3 cases there may be a common etiologic pattern of intranasal inoculation resulting from prolonged swimming in tepid lake water. Pathological findings in the first 2 cases were presented to the 1964 Scientific Session of… Expand
Primary amebic meningoencephalitis.
  • J. Seidel
  • Medicine
  • Pediatric clinics of North America
  • 1985
Primary amebic meningoencephalitis is a disease caused by the free-living amebae of the genera Naegleria or Acanthamoeba. The clinical course may result in death a few days after presentation or itExpand
Meningoencephalitis due to pathogenic free-living amoebae. Report of two cases.
During a four-month summer period, 390 cerebrospinalfluid specimens from 357 patients were studied for the presence of a free-living amoebae, resulting in the first case of nonlethal meningitis caused by the free- Living Amoeba astronyxis. Expand
Primary amebic meningoencephalitis.
Primary amebic meningoencephalitis is being recognized with increased frequency and appears to be worldwide and capable of producing epidemics and is universally fatal and at present without promise of therapy. Expand
A case of primary amebic meningoencephalitis in Zaria, Nigeria.
Subsequent identification based on morphologic features, flagellation, animal pathogenicity, and nuclear division proved conclusively that the ameba was Naegleria fowleri. Expand
Primary amebic meningoencephalitis: a silent killer.
A 9-year-old boy presented to the emergency department with headache, vomiting and lethargy, and despite aggressive management with amphotericin B and rifampin, he died 2 days later. Expand
Primary amebic meningoencephalitis. A survey in Virginia.
The data strongly suggest that at present, despite its epidemicity, the disease in Virginia appears to be endemic to one locale, namely an area in Chesterfield County defined by a 5-mile radius. Expand
Primary amebic meningoencephalitis diagnosed in the emergency department.
A previously healthy teenager, developed Naegleria meningoencephalitis after swimming in a freshwater public pool, which caused acute fulminating infection culminating in the death of the patient 36 hours after admission. Expand
Fatal case of Naegleria fowleri meningo-encephalitis in an infant: case report
A high index of suspicion is required in infants who manifest similarly to pyogenic meningitis but whose CSF shows no bacterial organisms so that a wet mount of a CSF sample can be done for early detection of Naegleria fowleri infection and appropriate intervention. Expand
Granulomatous brain tumor caused by Acanthamoeba. Case report.
The Acanthamoeba central nervous system infection presented in this girl as a discrete tumor without meningeal involvement or diffuse encephalitis, and a favorable outcome was obtained following total excision of the mass and treatment with ketoconazole. Expand
Successful treatment of primary amebic meningoencephalitis.
The fourth documented survivor of primary amebic meningoencephalitis, a young man with a history of waterskiing in a stagnant freshwater lake in northeastern Pennsylvania, is presented. EarlyExpand


Pathogenic Acanthamoeba (Hartmanella).
  • C. Culbertson
  • Biology, Medicine
  • American journal of clinical pathology
  • 1961
Experimental infection of mice and monkeys by Acanthamoeba.