Primary amebic meningoencephalitis due to Naegleria fowleri: An autopsy case in Japan
@article{Sugita1999PrimaryAM, title={Primary amebic meningoencephalitis due to Naegleria fowleri: An autopsy case in Japan}, author={Yasuo Sugita and Teruhiko Fujii and Itsurou Hayashi and Takachika Aoki and Toshiro Yokoyama and Minoru Morimatsu and Toshihide Fukuma and Yoshiaki Takamiya}, journal={Pathology International}, year={1999}, volume={49} }
Free‐living amebas represented by Naegleria fowleri, Acanthamoeba and Balamutia have been known to cause fatal meningoencephalitis since Fowler and Carter (1965) reported the first four human cases. An autopsy case of a 25‐year‐old female with primary amebic meningoencephalitis (PAM) due to Naegleria fowleri is described. Headache, lethargy and coma developed in this patient, and her condition progressed to death 8 days after the onset of clinical symptoms. Cerebral spinal fluid examination…
31 Citations
An autopsy case of amebic meningoencephalitis. The first Japanese case caused by Balamuthia mandrillaris
- MedicineNeuropathology : official journal of the Japanese Society of Neuropathology
- 2002
The first case of amebic meningoencephalitis caused by Balamuthia mandrillaris is reported in a 78‐year‐old Japanese woman with Sjögren's syndrome, who presented with high fever and lost consciousness and later developed neck stiffness and abducens palsy.
Autopsy case of amebic granulomatous meningoencephalitis caused by Balamuthia mandrillaris in Japan
- MedicinePathology international
- 2012
An autopsy case of Balamuthia encephalitis proven with polymerase chain reaction (PCR) and immunohistochemistry from paraffin‐embedded brain biopsy specimens is reported, suggesting PCR to amplify shorter segments of DNA may be of diagnostic value in detecting suspected cases of balamuthiasis in formalin‐fixed, paraff in‐fixed specimens.
Naegleria fowleri after 50 years: is it a neglected pathogen?
- Biology, MedicineJournal of medical microbiology
- 2016
It is important that investigations continue and that researchers collaborate to gain better understanding of the pathogenesis of this disease and, consequently, to improve the diagnosis and treatment of this devastating infection of the CNS.
Pathogenic free‐living amoebic encephalitis in Japan
- MedicineNeuropathology : official journal of the Japanese Society of Neuropathology
- 2019
Encephalitis caused by pathogenic free‐living amoebas should be added to the differential diagnosis of encephalitis patients because it does not show typical symptoms or laboratory findings.
Diagnosis of the primary amoebic meningoencephalitis due to Naegleria fowleri.
- Medicine, BiologyParasitology international
- 2005
Increasing Intracerebral Infections Caused by Free-Living Amebae in the United States and Worldwide
- Medicine, Biology
- 2010
The purpose of this review will be to describe the current epidemiology, pathophysiology, clinical manifestations, diagnosis, management, and prevention of free-living amebic infections of the CNS.
Granulomatous Amoebic Meningoencephalitis: A Diagnostic Dilemma
- Medicine
- 2013
MRI brain revealed multiple ill-defined heterogeneous intra-axial mass lesions seen in the left cerebellum, bilateral frontoparietal, left temporal and left occipital lobes that were appearing hypointense with faint hyperintensity within it on T1 and predominantly hyperintense on FLAIR/T2-weighted images.
Various brain-eating amoebae: the protozoa, the pathogenesis, and the disease
- Biology, MedicineFrontiers of Medicine
- 2021
Among various genera of free-living amoebae prevalent in nature, some members are identified as causative agents of human encephalitis, in which Naegleria fowleri followed by Acanthamoeba spp. and…
Origin and evolution of the worldwide distributed pathogenic amoeboflagellate Naegleria fowleri.
- Biology
- 2011
Effective PCR-based detection of Naegleria fowleri from cultured sample and PAM-developed mouse.
- BiologyEuropean journal of protistology
- 2015
References
SHOWING 1-10 OF 12 REFERENCES
Primary amebic meningoencephalitis.
- MedicineJAMA
- 1980
An 18-year-old man was admitted to the Tucson Medical Center, Tucson, Ariz, after a two-day history of headache, stiff neck, and fever, where he appeared healthy, alert, and fully oriented, although complaining of headache.
Successful treatment of primary amebic meningoencephalitis.
- MedicineArchives of internal medicine
- 1991
The fourth documented survivor of primary amebic meningoencephalitis, a young man with a history of waterskiing in a stagnant freshwater lake in northeastern Pennsylvania, is presented. Early…
Laboratory diagnosis of pathogenic free-living amoebas: Naegleria, Acanthamoeba, and Leptomyxid.
- MedicineClinics in laboratory medicine
- 1991
Free‐living, Amphizoic and Opportunistic Amebas
- BiologyBrain pathology
- 1997
Amebas belonging to the genera Naegleria, Acanthamoeba and Balamuthia are free‐living, amphizoic and opportunistic protozoa that are ubiquitous in nature. These amebas are found in soil, water and…
Acute Pyogenic Meningitis Probably Due to Acanthamoeba sp.: a Preliminary Report
- MedicineBritish medical journal
- 1965
A case of granulomatous meningo-encephalitis by Acanthamoeba
- Niigata Igaku 1987;
- 1987
An autopsy case of primary amoebic meningoencephalitis due to free living ameba (Leptomyxid)
- Neuropathology 1991;
- 1991
An autopsy case of primary amoebic meningoencephalitis
- Proc . Jpn Soc . Pathol
- 1996
Primary amebic meningoencephalitis and granulomatous encephalitis due to free-living amebas: Protozoology, epidemiology and neuropathology
- Neurol. Med. 1980;
- 1980
An autopsy case of primary amoebic meningoencephalitis
- Proc. Jpn Soc. Pathol
- 1996