Primary aldosteronism treated by trilostane (3 beta-hydroxysteroid dehydrogenase inhibitor).

@article{Nakada1985PrimaryAT,
  title={Primary aldosteronism treated by trilostane (3 beta-hydroxysteroid dehydrogenase inhibitor).},
  author={T. Nakada and T. Kazama and H. Koike and M. Yoshikawa and S. Ishikawa and T. Katayama},
  journal={Urology},
  year={1985},
  volume={25 2},
  pages={
          207-14
        }
}
  • T. Nakada, T. Kazama, +3 authors T. Katayama
  • Published 1985
  • Medicine
  • Urology
    • The practicability and tolerability of trilostane, a competitive inhibitor of 3 beta-hydroxysteroid-delta 5-dehydrogenase, for the therapy of primary aldosteronism was assessed in 1 patient with aldosterone-producing adenoma (APA) and 3 subjects with idiopathic adrenal hyperplasia (IHA). Trilostane afforded reduction of plasma levels of aldosterone, progesterone, deoxycorticosterone, 17-OH progesterone, cortisol, delta 4-androstenedione, and urinary excretion of 17-hydroxycorticosteroid… CONTINUE READING
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    Reversal of diuretic-induced secondary hyperaldosteronism and hypokalemia by trilostane, an inhibitor of adrenal steroidogenesis.
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    Therapeutic results of primary aldosteronism with special reference to renal or renovascular lesions
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    Trilostane, an inhibitor of 3β-hydroxysteroid dehydrogenase, has an agonistic activity on androgen receptor in human prostate cancer cells.
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    Cortisol, aldosterone, cortisol precursor, androgen and endogenous ACTH concentrations in dogs with pituitary-dependant hyperadrenocorticism treated with trilostane.
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    Effect of trilostane on serum concentrations of aldosterone, cortisol, and potassium in dogs with pituitary-dependent hyperadrenocorticism.
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    Results of clinical examinations, laboratory tests, and ultrasonography in dogs with pituitary-dependent hyperadrenocorticism treated with trilostane.
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    Trilostane treatment in dogs with pituitary-dependent hyperadrenocorticism.
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    Heterosteroids and drug research.
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    Trilostane in advanced breast cancer
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    Uneventful delivery following series of successive treatments for virilized Cushing syndrome due to adrenocortical carcinoma.
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