Primary adenosquamous carcinoma of the colon: Report of five cases

  title={Primary adenosquamous carcinoma of the colon: Report of five cases},
  author={Yingchun Dong and Jiandong Wang and Henghui Ma and Hangbo Zhou and Guang Ming Lu and Xiaojun Zhou},
  journal={Surgery Today},
Primary adenosquamous cell carcinomas (Ad-SCCs) of the colon and rectum are rare malignancies with a poor prognosis, in comparison to adenocarcinoma alone. Different roles of human papilloma virus (HPV) in its pathogenesis have been reported and the role of P16 in Ad-SCCs has not been explored. This report presents five cases of Ad-SCC of the colon to explore the clinicopathological features and the roles of P16, HPV 6/11, and 16/18. There was no confirmed evidence to support the relationship… CONTINUE READING
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