Primary Study on dnmts and mecp2 Expression in Lungs of Mice Induced by Formaldehyde

  title={Primary Study on dnmts and mecp2 Expression in Lungs of Mice Induced by Formaldehyde},
  author={Zhu Yan and Ke Ke and Wu Kai and Yang Xu},
  journal={2007 1st International Conference on Bioinformatics and Biomedical Engineering},
  • Zhu Yan, K. Ke, +1 author Yang Xu
  • Published 2007
  • Biology
  • 2007 1st International Conference on Bioinformatics and Biomedical Engineering
The purpose of the present study was to examine levels of mRNA for DNA methyltransferases (DNMTS) and methyl- CpG-binding proteins 2 (MeCP2 ) in the lung of mouse after middle-level gaseous formaldehyde exposure. Male mice were exposed to clean air or 3.0 mg/m3 formaldehyde for consecutive 72 h and the lungs were dissected for RNA extraction. The mRNA levels of dnmtl, tin in t3a and mecp2 gene were determined with semiquantitative RT-PCR. We observed that the mRNA expression of dnmtl and mecp2… Expand

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