Primary Sjögren Syndrome: Clinical and Immunologic Disease Patterns in a Cohort of 400 Patients

@article{GarcaCarrasco2002PrimarySS,
  title={Primary Sj{\"o}gren Syndrome: Clinical and Immunologic Disease Patterns in a Cohort of 400 Patients},
  author={Mario Garc{\'i}a-Carrasco and Manuel Ramos-Casals and Jos{\'e} Rosas and Lucio Pallar{\'e}s and Jaime Calvo-Al{\'e}n and Ricard Cervera and J. P. Rodriguez Font and Miguel Ingelmo},
  journal={Medicine},
  year={2002},
  volume={81},
  pages={270-280}
}
IntroductionSjogren syndrome (SS) is a systemic autoimmune disease that mainly affects the exocrine glands and usually presents as persistent dryness of the mouth and eyes due to functional impairment of the salivary and lacrimal glands (12). In the absence of an associated systemic autoimmune 
Primary Sjögren Syndrome in Primary Health Care
TLDR
Sjogren’s syndrome is characterized by lymphocytic infiltration of the exocrine glands, mainly the lacrimal and salivary glands, resulting in reduced secretory function and oral and ocular dryness.
Sjögren’s Syndrome and The Respiratory System: A Comprehensive Approach
Sjögren’s syndrome (SS) is an autoimmune connective tissue disease characterized by lymphocytic infiltration of exocrine glands leading to progressive inflammation and destruction. This condition
Sjögren's syndrome
Sjogren’s syndrome (SS) is a systemic autoimmune disease characterized by exocrine gland dysfunction and destruction, mainly localized at the level of salivary and lacrimal glands, leading to dryness
Primary Sjögren's syndrome: new clinical and therapeutic concepts.
TLDR
Patients with a predominantly extraepithelial expression should be managed differently from patients with predominantly periepithelial or sicca limited disease, and treatment will be based on muscarinic agonists for sicCA features and immunosuppressive/biological agents for extraglandular features.
Laboratory Abnormalities in Primary Sjögren’s Syndrome
TLDR
Sjogren’s syndrome is a systemic autoimmune disease that presents with sicca symptomatology of the main mucosa surfaces and may be complicated by the development of lymphoma.
Serologic features of primary Sjögren's syndrome: clinical and prognostic correlation.
TLDR
Patients with SS present a broad spectrum of serologic features and certain serological findings are highly correlated with specific clinical features, and can be used as prognostic markers.
Sicca features are the central clinical manifestations of Sjögren ’ s syndrome
TLDR
Patients with a predominantly extraepithelial expression should be managed differently from patients with predominantly periepithelial or sicca limited disease, and treatment will be based on muscarinic agonists for siccas features and immunosuppressive/biological agents for extraglandular features.
Comorbidities in Patients With Primary Sjögren's Syndrome and Systemic Lupus Erythematosus: A Comparative Registries‐Based Study
To compare the prevalence of the main comorbidities in 2 large cohorts of patients with primary Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE), with a focus on cardiovascular (CV)
Neurological Disorders in Primary Sjögren's Syndrome
TLDR
This paper endeavors to review the main clinical neurological manifestations in Sjögren syndrome, the physiopathology, and their therapeutic response.
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3 patients who developed lacrimal and salivary gland involvement at ages 3, 7 and 9, respectively are reported, finding that the one who began at age 3 is the youngest reported.
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TLDR
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TLDR
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