Primary Ovarian Insufficiency and Adolescent Vaccination.

  title={Primary Ovarian Insufficiency and Adolescent Vaccination.},
  author={Allison Naleway and Kathleen F. Mittendorf and Stephanie A. Irving and Michelle L Henninger and Bradley Crane and Ning Smith and Matthew F Daley and Julianne M Gee},
  volume={142 3}
BACKGROUND Published case series have suggested a potential association between human papillomavirus (HPV) vaccination and primary ovarian insufficiency (POI). We describe POI incidence and estimate POI risk after HPV; tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis, adsorbed (Tdap); inactivated influenza (II); and meningococcal conjugate (MenACWY) vaccination. METHODS We searched Kaiser Permanente Northwest electronic health records for outpatient diagnoses suggestive of… CONTINUE READING