Primary HIV-1 infection: a review of clinical manifestations, immunologic and virologic changes.

@article{Kaufmann1998PrimaryHI,
  title={Primary HIV-1 infection: a review of clinical manifestations, immunologic and virologic changes.},
  author={Gilbert R. Kaufmann and Christopher J Duncombe and John James Zaunders and Philip Cunningham and David A. Cooper},
  journal={AIDS patient care and STDs},
  year={1998},
  volume={12 10},
  pages={759-67}
}
In the past few years, major advances have been made in the field of primary HIV-1 infection. Several studies have reevaluated the clinical syndrome. The emergence of new molecular laboratory techniques has permitted a detailed analysis of viral dynamics and subsequent immunologic changes. Measurements of subsets of T-lymphocytes have allowed greater insight into the early pathogenesis of HIV-1 disease. There is now evidence that HIV-1-specific cytotoxic T-lymphocytes occur early during primary… CONTINUE READING