Primary Cilia: The Chemical Antenna Regulating Human Adipose-Derived Stem Cell Osteogenesis

@inproceedings{Bodle2013PrimaryCT,
  title={Primary Cilia: The Chemical Antenna Regulating Human Adipose-Derived Stem Cell Osteogenesis},
  author={Josephine C. Bodle and Candace Davida Rubenstein and Michelle Erzsebet Phillips and Susan H. Bernacki and Jie Qi and Albert J. Banes and Elizabeth G. Loboa},
  booktitle={PloS one},
  year={2013}
}
Adipose-derived stem cells (ASC) are multipotent stem cells that show great potential as a cell source for osteogenic tissue replacements and it is critical to understand the underlying mechanisms of lineage specification. Here we explore the role of primary cilia in human ASC (hASC) differentiation. This study focuses on the chemosensitivity of the primary cilium and the action of its associated proteins: polycystin-1 (PC1), polycystin-2 (PC2) and intraflagellar transport protein-88 (IFT88… CONTINUE READING

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  • 2017

References

Publications referenced by this paper.
SHOWING 1-10 OF 30 REFERENCES

Polycystins and primary cilia: primers for cell cycle progression.

  • Annual review of physiology
  • 2009
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