Primary CNS posttransplant lymphoproliferative disease (PTLD): an international report of 84 cases in the modern era.

@article{Evens2013PrimaryCP,
  title={Primary CNS posttransplant lymphoproliferative disease (PTLD): an international report of 84 cases in the modern era.},
  author={Andrew M Evens and Sylvain Choquet and Aimee R Kroll-Desrosiers and Deepa Jagadeesh and Sonali M Smith and Franck Morschhauser and V{\'e}ronique Leblond and Rajarshi Roy and Bruce Barton and Leo I Gordon and Maher K Gandhi and Daan Dierickx and David Schiff and Thomas Matthew Habermann and Ralf Trappe},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2013},
  volume={13 6},
  pages={1512-22}
}
We performed a multicenter, International analysis of solid organ transplant (SOT)-related primary central nervous system (PCNS) posttransplant lymphoproliferative disease (PTLD). Among 84 PCNS PTLD patients, median time of SOT-to-PTLD was 54 months, 79% had kidney SOT, histology was monomorphic in 83% and tumor was EBV+ in 94%. Further, 33% had deep brain involvement, 10% had CSF involvement, while none had ocular disease. Immunosuppression was reduced in 93%; additional first-line therapy… CONTINUE READING