Primary CNS T-cell Lymphomas: A Clinical, Morphologic, Immunophenotypic, and Molecular Analysis.

@article{Menon2015PrimaryCT,
  title={Primary CNS T-cell Lymphomas: A Clinical, Morphologic, Immunophenotypic, and Molecular Analysis.},
  author={Madhu P Menon and Alina Nicolae and Hillary G. Meeker and Mark A. Raffeld and Liqiang Xi and Armin G. Jegalian and Douglas Craig Miller and Stefania Pittaluga and Elaine S. Jaffe},
  journal={The American journal of surgical pathology},
  year={2015},
  volume={39 12},
  pages={1719-1729}
}
Primary central nervous system (CNS) lymphomas are relatively rare with the most common subtype being diffuse large B-cell lymphoma. Primary CNS T-cell lymphomas (PCNSTL) account for <5% of CNS lymphomas. We report the clinical, morphologic, immunophenotypic, and molecular characteristics of 18 PCNSTLs. Fifteen cases were classified as peripheral T-cell lymphoma, not otherwise specified, 2 of which were of γδ T-cell derivation and 1 was TCR silent; there was 1 anaplastic large cell lymphoma… CONTINUE READING