Primary Aldosteronism with Unusual Secretory Pattern1

  title={Primary Aldosteronism with Unusual Secretory Pattern1},
  author={Edward G. Biglieri and Paul E. Slaton and Sanford J. Kronfield and John Deck},
ABSTRACT An adrenocortical tumor that secreted normal amounts of aldosterone was successfully removed and the classic findings of hypokalemic alkalosis and hypertension in primary aldosteronism were corrected. The tumor failed to alter aldosterone excretion during potassium repletion, desoxycorticosterone administration, sodium restriction and pituitary suppression. Normal aldosterone secretion probably resulted from the degree of potassium depletion but was sufficient under this condition to… CONTINUE READING