Primary, secondary and tertiary myotubes in developing skeletal muscle: A new approach to the analysis of human myogenesis

@article{Draeger1987PrimarySA,
  title={Primary, secondary and tertiary myotubes in developing skeletal muscle: A new approach to the analysis of human myogenesis},
  author={Annette Draeger and Alan G. Weeds and RobinB. Fitzsimons},
  journal={Journal of the Neurological Sciences},
  year={1987},
  volume={81},
  pages={19-43}
}
Monoclonal antibodies to myosins have been used to describe and define the appearance and maturation of 3 different classes of myotube in developing human quadriceps muscle. Five monoclonal antibodies were used: (i) MAb A against human slow myosin heavy chain; (ii) MAb B against a myosin heavy chain present in most adult Type 2 fibres; (iii) MAb C against myosin heavy chain present in all mature and immature Type 2 fibres; (iv) MAb D, with similar reactivity to MAb C; (v) MAb E against human… CONTINUE READING
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