Pri-miR-17-92a transcript folds into a tertiary structure and autoregulates its processing.

Abstract

MicroRNAs control gene expression either by RNA transcript degradation or translational repression. Expressions of miRNAs are highly regulated in tissues, disruption of which leads to disease. How this regulation is achieved and maintained is still largely unknown. MiRNAs that reside on clustered or polycistronic transcripts represent a more complex case… (More)
DOI: 10.1261/rna.031039.111

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