Prevotella intermedia lipopolysaccharide stimulates release of nitric oxide by inducing expression of inducible nitric oxide synthase.

@article{Kim2004PrevotellaIL,
  title={Prevotella intermedia lipopolysaccharide stimulates release of nitric oxide by inducing expression of inducible nitric oxide synthase.},
  author={Sung-Jo Kim and M Ha and Eun Young Choi and J Choi and In-Soon Choi},
  journal={Journal of periodontal research},
  year={2004},
  volume={39 6},
  pages={424-31}
}
OBJECTIVES The purpose of this study was to examine the effects of lipopolysaccharide from Prevotella intermedia, a major cause of inflammatory periodontal disease, on the production of nitric oxide (NO) and expression of inducible nitric oxide synthase (iNOS) in the murine macrophage cell line RAW264.7. We also attempted to throw light on the signaling mechanisms involved in P. intermedia lipopolysaccharide-induced NO production. MATERIAL AND METHODS Lipopolysaccharide from P. intermedia… CONTINUE READING
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