Preventive effects of turmeric on the high-fat diet-induced hyperlipidaemia in mice associated with a targeted metabolomic approach for the analysis of serum lysophosphatidylcholine using LC-MS/MS

  title={Preventive effects of turmeric on the high-fat diet-induced hyperlipidaemia in mice associated with a targeted metabolomic approach for the analysis of serum lysophosphatidylcholine using LC-MS/MS},
  author={Shuna Jin and Chengwu Song and Sen Li and Yang Zhang and Chang Chen and Xin Zhou and Yong Xu and Yulin Feng and Zhiping Zhang and Hongliang Jiang},
  journal={Journal of Functional Foods},
Abstract Consumption of turmeric diets demonstrated preventive effects on high-fat diet (HFD) induced hyperlipidaemia. However, the preventive effects on serum lysophosphatidylcholines (Lyso PCs) have not yet been studied. For this study, an approach for characterization of Lyso PCs in mice serum using LC-QTOF-MS/MS was developed. The preventive effects of turmeric diets were evaluated on quantitative changes of individual Lyso PCs in mice serum by LC-QTRAP-MS/MS. As a result, 74 Lyso PCs were… Expand
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