Preventive effects of quercetin against benzo[a]pyrene-induced DNA damages and pulmonary precancerous pathologic changes in mice.

@article{Jin2006PreventiveEO,
  title={Preventive effects of quercetin against benzo[a]pyrene-induced DNA damages and pulmonary precancerous pathologic changes in mice.},
  author={Nian-zu Jin and Yan-ping Zhu and Jian-wei Zhou and Li Mao and Ren-cheng Zhao and Tai-hui Fang and Xinru Wang},
  journal={Basic & clinical pharmacology & toxicology},
  year={2006},
  volume={98 6},
  pages={593-8}
}
The aim of this study was to investigate the preventive effects of quercetin against benzo[a]pyrene-induced blood lymphocyte DNA damages and pulmonary precancerous pathologic changes in mice, and to reveal the potential mechanism behind these effects. In this study, mice in quercetin-treated groups were given quercetin for 90 days. After one week of treatment, mice in the quercetin-treated groups and the positive control group received a single intraperitoneal dose of benzo[a]pyrene (100 mg/kg… CONTINUE READING

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