Preventive effects of mycobacteria and their culture supernatants against asthma development in BALB/c mice

@inproceedings{Han2010PreventiveEO,
  title={Preventive effects of mycobacteria and their culture supernatants against asthma development in BALB/c mice},
  author={Eui-Ryoung Han and Inseon S. Choi and Sun-Ho Eom and Hwa-Jung Kim},
  booktitle={Allergy, asthma & immunology research},
  year={2010}
}
PURPOSE Live Mycobacterium bovis Bacille Calmette-Guérin (BCG) has a suppressive effect on asthma, but its use in clinical practice may be limited due to adverse reactions. To develop a product that is effective for suppressing asthma with minimal adverse reactions, we investigated whether the heat-killed body or culture supernatants of mycobacteria could also prevent asthma development. METHODS Female BALB/c mice were treated with live BCG, the heat-killed body, or culture supernatants of… CONTINUE READING

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