Preventive effects of Cladosiphon fucoidan against Helicobacter pylori infection in Mongolian gerbils.

@article{Shibata2003PreventiveEO,
  title={Preventive effects of Cladosiphon fucoidan against Helicobacter pylori infection in Mongolian gerbils.},
  author={Hideyuki Shibata and Masaki Iimuro and Naoaki Uchiya and Toshihiko Kawamori and Masato Nagaoka and Sadao Ueyama and Shusuke Hashimoto and Teruo Yokokura and Takashi Sugimura and Keiji Wakabayashi},
  journal={Helicobacter},
  year={2003},
  volume={8 1},
  pages={59-65}
}
BACKGROUND Recently, the acquisition by Helicobacter pylori of resistance to antibiotics has become a serious problem. Therefore, nonantibiotic substances are required to diminish H. pylori-induced gastric lesions. In the present study, the effects of Cladosiphon fucoidan were examined in terms of H. pylori attachment to porcine gastric mucin in vitro and Helicobacter pylori-induced gastritis in vivo. METHODS The inhibitory effect of Cladosiphon fucoidan and other polysaccharides on H. pylori… CONTINUE READING