Preventive effect of co-administration of water containing magnesium ion on indomethacin induced lesions of gastric mucosa in adjuvant-induced arthritis rat.

Abstract

It is well known that nonsteroidal anti-inflammatory drugs (NSAIDs) have significant side effects, such as gastroenteropathy, and that rheumatoid arthritis patients taking NSAIDs are more susceptible to NSAIDs-induced gastric lesions as compared with patients with other diseases. We demonstrate the preventive effect of the co-administration of bittern water… (More)

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@article{Nagai2009PreventiveEO, title={Preventive effect of co-administration of water containing magnesium ion on indomethacin induced lesions of gastric mucosa in adjuvant-induced arthritis rat.}, author={Noriaki Nagai and Takashi Fukuhata and Yoshimasa Ito and Shigeyuki Usui and Kazuyuki Hirano}, journal={Biological & pharmaceutical bulletin}, year={2009}, volume={32 1}, pages={116-20} }