Preventive effect of Ginkgo biloba extract (GBB) on the lipopolysaccharide-induced expressions of inducible nitric oxide synthase and cyclooxygenase-2 via suppression of nuclear factor-kappaB in RAW 264.7 cells.

@article{Park2006PreventiveEO,
  title={Preventive effect of Ginkgo biloba extract (GBB) on the lipopolysaccharide-induced expressions of inducible nitric oxide synthase and cyclooxygenase-2 via suppression of nuclear factor-kappaB in RAW 264.7 cells.},
  author={Young-Mi Park and Jong-Heon Won and K. Yun and Jong-Hoon Ryu and Yongnam Han and Seung-Ki Choi and K. Lee},
  journal={Biological & pharmaceutical bulletin},
  year={2006},
  volume={29 5},
  pages={
          985-90
        }
}
  • Young-Mi Park, Jong-Heon Won, +4 authors K. Lee
  • Published 2006
  • Biology, Medicine
  • Biological & pharmaceutical bulletin
  • During our ongoing efforts to identify bioactive natural products with anti-inflammatory activity, we produced an extract from Ginkgo biloba (GBB) which contains higher levels of the active principles terpene and biflavonoid than EGb, the standard commercially available extract. In the present study, we examined and compared the effects of these two extracts on lipopolysaccharide (LPS)-induced nitric oxide (NO) and prostaglandin E2 (PGE2) production by the RAW 264.7 macrophage cell line. Our… CONTINUE READING

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