Preventive actions of a high dose of glucosamine on adjuvant arthritis in rats

@article{Hua2004PreventiveAO,
  title={Preventive actions of a high dose of glucosamine on adjuvant arthritis in rats},
  author={Jianyi Hua and Shiori Suguro and Shin-ichi Hirano and Koji Sakamoto and Isao Nagaoka},
  journal={Inflammation Research},
  year={2004},
  volume={54},
  pages={127-132}
}
Abstract.Objective: Glucosamine, a naturally occurring amino monosaccharide has been used to treat or prevent osteoarthritis in humans. In this study, we evaluated the effect of glucosamine on rat adjuvant arthritis, a model of rheumatoid arthritis.Materials and methods: Adjuvant arthritis was induced in male Wistar rats by injection of Freund’s complete adjuvant (FCA) into the right hind paw, and 300 mg/kg of glucosamine, an extra-dose compared with a regular dose for osteoarthritis patients… Expand
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