Prevention of ventilator-associated pneumonia by oral decontamination: a prospective, randomized, double-blind, placebo-controlled study.

@article{Bergmans2001PreventionOV,
  title={Prevention of ventilator-associated pneumonia by oral decontamination: a prospective, randomized, double-blind, placebo-controlled study.},
  author={D C Bergmans and Marc J. M. Bonten and Carlo A J M Gaillard and Jennifer Paling and Siebe van der Geest and Frank H. van Tiel and A. J. M. M. Beysens and Peter W de Leeuw and Ellen E. Stobberingh},
  journal={American journal of respiratory and critical care medicine},
  year={2001},
  volume={164 3},
  pages={382-8}
}
UNLABELLED Colonization of the intestinal tract has been assumed to be important in the pathogenesis of ventilator-associated pneumonia (VAP), but relative impacts of oropharyngeal, gastric, or intestinal colonization have not been elucidated. Our aim was to prevent VAP by modulation of oropharyngeal colonization, without influencing gastric and intestinal colonization and without systemic prophylaxis. In a prospective, randomized, placebo-controlled, double-blind study, 87 patients received… CONTINUE READING

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