Prevention of tunneled hemodialysis catheter-related infections using catheter-restricted filling with gentamicin and citrate: a randomized controlled study.

@article{Dogra2002PreventionOT,
  title={Prevention of tunneled hemodialysis catheter-related infections using catheter-restricted filling with gentamicin and citrate: a randomized controlled study.},
  author={Gursharan K Dogra and Helen Herson and Brian Hutchison and Ashley B Irish and Christopher H. Heath and Clay Golledge and Grant Luxton and Harry Moody},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2002},
  volume={13 8},
  pages={2133-9}
}
Tunneled catheters are widely used for the provision of hemodialysis. Long-term catheter survival is limited by tunneled catheter-related infections (CRI). This study assesses the efficacy of catheter-restricted filling with gentamicin and citrate in preventing CRI in hemodialysis patients. A double-blind randomized study was conducted to compare heparin (5000 U/ml) with gentamicin/citrate (40 mg/ml and 3.13% citrate; ratio 2:1) as catheter-lock solutions. A total of 112 tunneled catheters in… CONTINUE READING