Prevention of transplacental transmission of moderate-virulent classical swine fever virus after single or double vaccination with an E2 subunit vaccine.

@article{Smit2000PreventionOT,
  title={Prevention of transplacental transmission of moderate-virulent classical swine fever virus after single or double vaccination with an E2 subunit vaccine.},
  author={Abraham J. de Smit and Annemarie Bouma and E P de Kluijver and Caroline Terpstra and Rob J. M. Moormann},
  journal={The Veterinary quarterly},
  year={2000},
  volume={22 3},
  pages={
          150-3
        }
}
The use of a vaccine against classical swine fever virus (CSFV) during an outbreak of CSF should lead to a reduction in the horizontal or vertical transmission of CSFV. The reduction of vertical, i.e. transplacental, transmission of a moderate-virulent strain of CSFV from the sow to its offspring was studied in sows vaccinated once or twice with a CSFV E2 subunit vaccine. Two groups of nine sows were vaccinated with one PD95 dose of the E2 subunit vaccine, approximately four weeks before… CONTINUE READING
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Yeast-expressed classical swine fever virus glycoprotein E2 induces a protective immune response.

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