Prevention of trabecular bone loss in the mandible of ovariectomized rats.

@article{Jiang2004PreventionOT,
  title={Prevention of trabecular bone loss in the mandible of ovariectomized rats.},
  author={Guizhen Jiang and Hiroko Matsumoto and Junichi Yamane and Noboru Kuboyama and Yoshiaki Akimoto and Akira Fujii},
  journal={Journal of oral science},
  year={2004},
  volume={46 2},
  pages={75-85}
}
The effect of therapeutic agents on trabecular bone loss in the mandible was investigated in ovariectomized rats. Eighty-seven Wistar SPF female rats were ovariectomized (OVX) or given a sham operation (Sham), and maintained on a diet containing 0.1% calcium. Four weeks later, groups of OVX rats were treated with estriol (E3), calcitonin (CT), etidronate, or 2-carboxyethylgermanium sesquioxide (Ge-132). The Basal group was maintained on a diet containing 1.0% calcium, and the OVX and sham… CONTINUE READING