Prevention of the hematopoietic toxicity associated with zidovudine in vivo with IL-1 alone or in combination with GM-CSF administered to normal mice.

@article{Gallicchio1993PreventionOT,
  title={Prevention of the hematopoietic toxicity associated with zidovudine in vivo with IL-1 alone or in combination with GM-CSF administered to normal mice.},
  author={Vincent S. Gallicchio and Nedda K Hughes and Kam Fai Tse and Hans Gaines},
  journal={Growth factors},
  year={1993},
  volume={9 3},
  pages={177-83}
}
We studied the effect of interleukin-1 (IL-1 alpha) either alone or administered with GM-CSF on the induction of hematopoietic toxicity associated with zidovudine (AZT) in vivo, as determined by peripheral blood indices, and assays of hematopoietic progenitors, i.e., erythroid (BFU-E), myeloid (CFU-GM), and megakaryocyte (CFU-Meg) cultured from bone marrow… CONTINUE READING