Prevention of symptomatic vasospasm by topically applied Nimodipine

@article{Auer1982PreventionOS,
  title={Prevention of symptomatic vasospasm by topically applied Nimodipine},
  author={Univ.-Doz. Dr. L. M. Auer and Dr. Z. Ito and Dr. Atsuko Suzuki and Dr. H. Ohta},
  journal={Acta Neurochirurgica},
  year={1982},
  volume={63},
  pages={297-302}
}
A 2.4×10−5M solution of the Calcium-antagonist Nimodipine was administered to the exposed cerebral vessels in 17 patients intraoperatively clipping of a ruptured aneurysm. The interval between subarachnoid haemorrhage and operation was 48 to 72 hours. The CT investigation had revealed blood accumulation in the basal cisterns in all cases. Vasodilatation was observed in all instances; the percentage being greater in small vessels as compared to large vessels. Postoperatively, a neurological… CONTINUE READING
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