Prevention of symptomatic seasonal influenza in 2005-2006 by inactivated and live attenuated vaccines.

@article{Ohmit2008PreventionOS,
  title={Prevention of symptomatic seasonal influenza in 2005-2006 by inactivated and live attenuated vaccines.},
  author={Suzanne E. Ohmit and John C Victor and Esther R Teich and Rachel K Truscon and Judy R Rotthoff and Duane W Newton and Sarah A Campbell and Matthew L. Boulton and Arnold S. Monto},
  journal={The Journal of infectious diseases},
  year={2008},
  volume={198 3},
  pages={312-7}
}
BACKGROUND The efficacy of influenza vaccines may vary annually. In 2004-2005, when antigenically drifted viruses were circulating, a randomized, placebo-controlled trial involving healthy adults showed that inactivated vaccine appeared to be efficacious, whereas live attenuated vaccine appeared to be less so. METHODS In 2005-2006, we continued our trial, examining the absolute and relative efficacies of the live attenuated and inactivated vaccines in preventing laboratory-confirmed… CONTINUE READING
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