Prevention of renal hypertension in the rat by neuropeptide Y.

  title={Prevention of renal hypertension in the rat by neuropeptide Y.},
  author={Bernard Waeber and Dominique Ev{\'e}quoz and Jean François Aubert and J P Fl{\"u}ckiger and Lucienne Juillerat and Juerg Nussberger and Hans Rudolf Alfred Brunner},
  journal={Journal of hypertension},
  volume={8 1},
Neuropeptide Y is known to enhance blood pressure responsiveness to various constrictors, including angiotensin II, and to suppress renin secretion. This study was undertaken to assess the effect of neuropeptide Y on the development of two-kidney, one clip renal hypertension. Normotensive rats either had a silver clip placed on the left renal artery or were sham-operated upon. An osmotic minipump, which was connected via a catheter to a jugular vein, was implanted subcutaneously in all rats… CONTINUE READING