Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate.

@article{Brancazio2003PreventionOR,
  title={Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate.},
  author={Leo R. Brancazio and Amy P. Murtha and R Phillps Heine},
  journal={The New England journal of medicine},
  year={2003},
  volume={348 24},
  pages={2379-85}
}
BACKGROUND Women who have had a spontaneous preterm delivery are at greatly increased risk for preterm delivery in subsequent pregnancies. The results of several small trials have suggested that 17 alpha-hydroxyprogesterone caproate (17P) may reduce the risk of preterm delivery. METHODS We conducted a double-blind, placebo-controlled trial involving pregnant women with a documented history of spontaneous preterm delivery. Women were enrolled at 19 clinical centers at 16 to 20 weeks of… CONTINUE READING
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