Prevention of photoimmunosuppression and photocarcinogenesis by topical nicotinamide.

  title={Prevention of photoimmunosuppression and photocarcinogenesis by topical nicotinamide.},
  author={Helen L. Gensler},
  journal={Nutrition and cancer},
  volume={29 2},
Ultraviolet (UV) B irradiation leads to a potent immunosuppression of the capacity to reject syngeneic, antigenic tumors. If this immunosuppression is critical for the development of most skin tumors, then its prevention should result in prevention of photocarcinogenesis. We previously showed a correlation between the inhibition of photoimmunosuppression and prevention of photocarcinogenesis by dl-alpha-tocopherol, tannic acid, or alpha-difluoromethylornithine. The current study was designed to… CONTINUE READING


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