Prevention of palatable diet-induced hyperphagia in rats by central injection of a VEGFR kinase inhibitor.

@article{Branch2015PreventionOP,
  title={Prevention of palatable diet-induced hyperphagia in rats by central injection of a VEGFR kinase inhibitor.},
  author={Audrey Branch and Anastasia M. Bobilev and Nuria Waddington Negrao and Haini Cai and Ping Shen},
  journal={Behavioural brain research},
  year={2015},
  volume={278},
  pages={506-13}
}
Our previous studies have demonstrated a critical role of a VEGFR-like signaling pathway in hunger-driven overeating of sugar-rich food in Drosophila larvae. In the current study, we investigate whether the VEGFR signaling mechanism plays a similar role in the feeding behavior of vertebrates using male Sprague Dawley rats. Young rats were treated… CONTINUE READING