Prevention of osteoporosis after cardiac transplantation: a prospective, longitudinal, randomized, double-blind trial with calcitriol.

@article{Stempfle1999PreventionOO,
  title={Prevention of osteoporosis after cardiac transplantation: a prospective, longitudinal, randomized, double-blind trial with calcitriol.},
  author={H U Stempfle and Christiane Werner and S Echtler and Uli Wehr and Walter Albert Rambeck and Uwe Siebert and Peter A Uberfuhr and Christiane E. Angermann and Karl Theisen and Roland G{\"a}rtner},
  journal={Transplantation},
  year={1999},
  volume={68 4},
  pages={523-30}
}
BACKGROUND Accelerated bone loss is a well-recognized complication after cardiac transplantation (HTx) due to immunosuppressive therapy. The purpose of this prospective, longitudinal, randomized, placebo-controlled, double-blind study was to investigate the effect of calcitriol (1,25-dihydroxyvitamin D3) in the prevention of bone loss and fracture rate after HTx. METHODS Basic therapy included 1000 mg of calcium daily and sex hormone replacement in hypogonadal patients. A total of 132… CONTINUE READING

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