Prevention of motoneuron death by adenovirus-mediated neurotrophic factors.

@article{Ribotta1997PreventionOM,
  title={Prevention of motoneuron death by adenovirus-mediated neurotrophic factors.},
  author={Minerva Gim{\'e}nez y Ribotta and Fr{\'e}d{\'e}ric Revah and Laurent Pradier and Isabelle Loquet and Jacques Mallet and Alain Privat},
  journal={Journal of neuroscience research},
  year={1997},
  volume={48 3},
  pages={281-5}
}
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of motoneurons, and has no effective treatment. Experimental studies in rodents have shown that motoneurons respond to a variety of molecules including brain-derived neurotrophic factor (BDNF). and the glial-cell line-derived neurotrophic factor (GDNF… CONTINUE READING